Down Syndrome Research Forum 2023
The Down Syndrome Research Forum 2023 will be held online on Thursday 27th and Friday 28th April, 2023.Learn more
Our research explores how children with Down syndrome develop and learn, and identifies more effective teaching approaches and therapies. We have a unique focus and a successful 40-year track record in delivering research that today is improving educational outcomes for many thousands of young people with Down syndrome around the world.
Over the past 40 years, our studies have delivered important insights into speech and language, memory, reading, number and mathematics, social skills, education, sleep and behavior for children with Down syndrome. Our research has repeatedly demonstrated the potential of children with Down syndrome to learn more when given the opportunity and appropriate support.
Ensuring research makes a real difference
We ensure that our research delivers benefits for people with Down syndrome living today by identifying and evaluating evidence-based interventions, and by disseminating our findings to families and professionals worldwide.
Our #Education21 campaign highlights how educational research is helping us to better understand the needs of young people with Down syndrome and how it is improving outcomes for many thousands of children today.Find out more
A successful track record spanning 40 years
For over 40 years our work has delivered key advances in our understanding of the reading, language, speech and memory difficulties experienced by children with Down syndrome, and pioneered techniques that improve development and levels of educational achievement.
In the early 1980s, our research team was the first to identify that young children with Down syndrome could learn to read and could learn to read surprisingly well at an early age. Since then, we have sponsored and undertaken research in many areas of development for young people with Down syndrome, including speech and language, memory, reading, number and mathematics, social skills, education, sleep and behavior.
Our research, resources and services have played a significant role in improving education for children with Down syndrome. Only 30 year ago, it was widely thought that young people with Down syndrome could not learn to read. Today, some 10%-20% of children with Down syndrome in mainstream primary schools are reading as well as their typical classmates.
"The charity has had a profound impact on the Down syndrome research and practice community for the past three decades. It combines a scientifically grounded approach to educating individuals with Down syndrome with a passion for improving the life of each child." (Professor Deborah Fidler, Colorado State University, USA).
Our unique focus
We focus on practical scientific studies of young people with Down syndrome that identify their precise learning difficulties and that evaluate teaching approaches and therapies designed to meet their particular needs.
We take a 'real world' view of development, studying learning for young people with Down syndrome in everyday family life and in school. Many things influence development, including our genes, our families and communities, and the opportunities that we are offered. Our research examines all of these factors in the context of the complex and cumulative processes of human development.
We have recently completed two of the first randomized controlled trials of targeted interventions for children with Down syndrome.
The first of these trials found that carefully structured daily reading and language teaching can improve reading and language development for primary schoolchildren with Down syndrome. We are now publishing a handbook and supplementary resources to support use of the intervention in schools worldwide. The second recent randomized controlled trial evaluated computer-based adaptive memory training program with children with Down syndrome.
Other recent or ongoing research includes studies of early language development, the emergence of of autism and autism-like behaviors in young children with Down syndrome, improving early problem solving skills, teaching early phonics skills, early number teaching approaches, and attention skills.
"The charity is now central to the worldwide understanding and sharing of research from many academics and longer-term experience of those working with generations of children with Down syndrome." (New Philanthropy Capital, London, UK)
Recent and selected research publications
- Burgoyne, K., Buckley, S.J. & R. Baxter. R. (2021) Speech production accuracy in children with Down syndrome: relationships with hearing, language, and reading ability and change in speech production accuracy over time. Journal of Intellectual Disability Research, 65, 1021-1032. doi.org/10.1111/jir.12890
- de Graaf, G., Buckley F., Skotko B.G. (2021) Estimation of the number of people with Down syndrome in Europe. European Journal of Human Genetics 29, 402-410. doi.org/10.1038/s41431-020-00748-y
- Mason-Apps, E. , Stojanovik, V. , Houston-Price, C. , Seager, E. , Buckley, S. (2020) Do infants with Down syndrome show an early receptive language advantage? Journal of Speech, Language and Hearing Research , 63 (2). pp. 585-598. doi.org/10.1044/2019_JSLHR-19-00157
- Mason-Apps, E. , Stojanovik, V. , Houston-Price, C. , Buckley, S. (2018) Longitudinal predictors of early language in infants with Down syndrome: a preliminary study. Research in Developmental Disabilities, 81 pp. 37-51. doi.org/10.1016/j.ridd.2017.12.021
- de Graaf, G., Buckley, F., Dever, J., Skotko, B.G. (2017). Estimation of live birth and population prevalence of Down syndrome in nine U.S. states. American Journal of Medical Genetics, Part A, Early view. https://dx.doi.org/10.1002/ajmg.a.38402
- de Graaf, G., Buckley F., Skotko B.G. (2017). Estimation of the number of people with Down syndrome in the United States. Genetics in Medicine, 19(4), 437-447. https://10.1038/gim.2016.127
- de Graaf, G., Buckley, F., Skotko, B.G. (2016). Live births, natural losses, and elective terminations with Down syndrome in Massachusetts. Genetics in Medicine, 18, 459-466. https://10.1038/gim.2016.15
- de Graaf, G., Buckley, F., Skotko, B.G. (2015). Estimates of the live births, natural losses and elective terminations with down syndrome in the United States. American Journal of Medical Genetics, Part A, 167A, 756-767. https://dx.doi.org/10.1002/ajmg.a.37001
- Mengoni, S. E., Nash, H. & Hulme, C. (2014). Learning to read new words in individuals with Down syndrome: Testing the role of phonological knowledge. Research in Developmental Disabilities, 35, 1098-1109. https://doi.org/10.1016/j.ridd.2014.01.030
- Burgoyne, K., Baxter, R. & Buckley, S. (2014). Supporting the literacy skills of children with Down syndrome. Chapter in R. Faragher and B. Clarke (Eds.), Educating Learners with Down Syndrome. pp 195-220. Oxford: Routledge Education.
- Ashworth, A., Hill, C.M., Karmiloff-Smith, A.& Dimitriou, D. (2014) The Importance of Sleep: Attentional Problems in School-Aged Children with Down syndrome and Williams syndrome. Behavioral Sleep Medicine, 12, 1-17. https://dx.doi.org/10.1080/15402002.2014.940107
- Steele, A., Scerif, G., Cornish, K. & Karmiloff-Smith, A. (2013) Learning to read in Williams syndrome and Down syndrome: syndrome-specific precursors and developmental trajectories. Journal of Child Psychology and Psychiatry, 54(7), 754-762. https://doi.org/10.1111/jcpp.12070
- Mengoni, S. E., Nash, H. & Hulme, C. (2013). The benet of orthographic support for oral vocabulary learning in children with Down syndrome. Journal of Child Language, 40, pp 221-243 https://dx.doi.org/10.1017/S0305000912000396
- Cornish, K.,A. Steele, A., Rondinelli Cobra Monteiro, C., Karmiloff-Smith, A. & Scerif, G. (2012) Attention deficits predict phenotypic outcomes in syndrome-specific and domain-specific ways. Frontiers in Psychology 3, 227. https://dx.doi.org/10.3389/fpsyg.2012.00227
- Burgoyne, K., Duff, F., Snowling, M., Buckley, S. & Hulme, C. (2013). Training phoneme blending skills in children with Down syndrome. Child Language Teaching and Therapy, 29(3), 273-290. https://dx.doi.org/10.1177/0265659012474674
- Bennett S, Holmes J and Buckley S (2013). Computerized memory training leads to sustained improvement in visuospatial short term memory skills in children with Down syndrome. American Journal on Intellectual and Developmental Disabilities, 118(3), 179-192. https://doi.org/10.1352/1944-7558-118.3.179
- Ashworth, A., Hill, C.M., Karmiloff-Smith, A.& Dimitriou, D. (2013) Cross syndrome comparison of sleep problems in children with Down syndrome and Williams syndrome Research in Developmental Disabilities, 34, 1572-1580. https://dx.doi.org/10.1111/desc.12383
- Steele, A., Karmiloff-Smith, A. Cornish, K. & Scerif, G. (2012) The Multiple Subfunctions of Attention: Differential Developmental Gateways to Literacy and Numeracy. Child Development, 83, 6, 2028-2041. https://dx.doi.org/10.1111/j.1467-8624.2012.01809.x
- Buckley, S. (2010) Health research, the needs of persons with Down syndrome and their families. In: R Urbano (Ed.) International Review of Research in Mental Retardation. Pp 295- 306. Academic Press.
- Burgoyne, Duff, Clarke, Snowling, Buckley, Hulme (2012) Efficacy of a reading and language intervention for children with Down syndrome: an RCT. Journal of Child Psychology and Psychiatry, 53, 1044-1053. https://dx.doi.org/10.1111/j.1469-7610.2012.02557.x
- Buckley, S.J. (2008). The development of babies with Down syndrome. In S J Skallerup (Ed.) Babies with Down syndrome. (pp 169-198). 3rd Edition. Bethesda: Woodbine House.
- Buckley, S. J. & Johnson-Glenberg, M.C. (2008) Increasing literacy learning in Down syndrome and Fragile X syndrome. In J. E. Roberts, R.S. Chapman & S.F. Warren (Eds.) Speech and Language Development and Intervention in Down Syndrome and Fragile X Syndrome. (pp 233-254). Baltimore: Paul H. Brookes.
- Buckley, S., Bird, G., Sacks, B. & Archer, T. (2007). Mainstream or special education for teenagers with Down syndrome. In Jean-Adolphe Rondal & Alberto Rasore-Quartino (Eds.). Therapies and Rehabilitation in Down Syndrome. Chichester: Wiley.
- Buckley, S. (2003). Literacy and Language. In Rondal, J. & Buckley, S. J. (Eds) Speech and Language Intervention in Down syndrome. (pp. 132-153). London: Whurr.
- Buckley, S. & Bird, G. (2002). Cognitive development and education: Perspectives on Down syndrome from a twenty-year research programme. In M.Cuskelly, A. Jobling, & S. Buckley (Eds.), Down syndrome across the life span (pp. 66-80). London: Whurr.